A peer-reviewed pilot study, published in Frontiers in Sleep (2025), was conducted by investigators from the Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women’s Hospital and the Division of Sleep Medicine, Harvard Medical School.
The study evaluated adults who self-identified as “hot sleepers” before and after using sheets made of 100% cotton treated with Xirotex™ Cool technology. Results demonstrated statistically significant improvements in overall sleep quality and duration, as well as measurable reductions in the frequency and severity of night sweats.

In a peer-reviewed clinical pilot study, researchers analyzed over 2,600 nights of sleep data to assess how temperature-regulating sheets made with Xirotex™ Cool fabric affected sleep quality in adults who sleep hot.
Developed to help reduce heat accumulation during sleep, the sheets were studied for their ability to promote comfort among adults who often wake from feeling overheated.

“Results of this pilot study reveal that, after introducing the cooling bed sheets, there was a significant improvement in sleep quality, as measured by both subjective sleep quality scores and sleep duration. These findings suggest that temperature regulation during sleep may play a critical role in improving overall sleep health and comfort.”
📄 Source: Frontiers in Sleep — A non-randomized pre-post pilot study of cooling bed sheets in hot sleeping people
Lara Smith, Founder and CEO of LUSOMÉ recaps our clinical trial results of LUSOMÉ Temperature Regulating sheets—highlighting XIROTEX™ Cool technology.
Lusomé is committed to advancing evidence-based innovation in sleep wellness through collaborations with researchers and institutions dedicated to improving women’s health.
The findings suggest that the use of temperature-regulating sheets may support better sleep in adults who experience night sweats or overheating during the night. Participants in the study experienced longer sleep duration, improved subjective sleep quality, and reduced night-sweat frequency. The results provide early evidence that textile-based temperature regulation may be a promising strategy to improve comfort and rest among individuals who sleep hot.
Read the Full Peer-Reviewed Study in Frontiers in SleepThis page is intended for informational purposes only. It summarizes findings from an independent, peer-reviewed study and does not constitute medical advice. The study evaluated one type of Lusomé bed sheet using Xirotex™ Cool fabric; results may not generalize to all products or individuals.